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KMID : 0876319990010020141
Cachon Medical Journal
1999 Volume.1 No. 2 p.141 ~ p.145
A Case of Ocular Tilt Reaction Due to Rostral Mesencephalic Lesion
Kang Sung-Soo

Yun Chang-Bon
Kim Myung-Kwon
Park Hyeon-Mi
Lee Seon-Kyu
Paik Hae-Jung
Shin Dong-Jin
Abstract
Background & Significance: Ocular tilt reaction (OTR) is a central vestibular disorder involving the vertical vestibule-ocular reflex in the roll plane. It is based upon both utricular and vertical canal inputs and is mediated by the graviceptive pathways from the labyrinths via pontomedullary vestibular nuclei to the rostral midbrain tegmentum. We report a case of OTR due to rostral midbrain lesion.
Case: A 20-year-old female was admitted due to sudden onset diplopia and headache. She showed a complex ocular motor syndrome that was associated with bilateral nuclear type oculomotor nerve palsy, limitation of vertical gaze and impaired light reflex (efferent type). Brain MRI revealed the rostral midbrain lesion (localized intraventricular
hemorrhage, 3rd ventricle, surrounding edema). Angiographic findings are consistent with Moyamoya disease or Moyamoya syndrome. After 3 weeks, she showed OTR. Her limitation of vertical gaze was partially improved.
Conslusion: We report one patient with rostral midbrain lesion (intraventricular hemorrhage), who showed OTR during the resolving stage of hemorrhage.
KEYWORD
Moyamoya disease, Moyamoya syndrome, OTR (Ocular tilt reaction)
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